Are Polycomb Group Bodies Gene Silencing Factories?
نویسندگان
چکیده
Polycomb group (PcG) proteins mediate long-range associations between Hox genes, which correlate with gene repression in vivo. Bantignies et al. (2011) identify a physiological role for the nuclear localization of Hox genes in PcG-mediated gene silencing, strengthening the evidence that nuclear positioning regulates gene expression.
منابع مشابه
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عنوان ژورنال:
- Cell
دوره 144 شماره
صفحات -
تاریخ انتشار 2011